Senior R&D Chemist
1 month ago
Senior R&D Chemist
12 month contract
Location: Swords Campus
ABOUT US?
SK biotek Ireland, an SK pharmteco company, is a global Contract Development and Manufacturing organisation (CDMO) with state-of-the-art facilities in Korea, US, France and Ireland. We are part of the wider SK Inc. with revenues of $95 billion in 2020. Our mission is to ‘make what matters for a healthy, happier world’, from grams to tonnes. The Swords Campus has led the way in the development, scale-up and commercial manufacture of Active Pharmaceuticals Ingredients (APIs), Highly Potent Active Pharmaceuticals Ingredients and Chemical Intermediates for almost 60 years. With a talented workforce, exceptional technical capabilities, and facilities we have made some of the world’s most important medicines and continue to do so. Further information on SK pharmteco can be found at .
Current Need:
Cpl in partnership with SK biotek Ireland are seeking to recruit a Senior R&D Chemist, on a 12 month contract. This position is based at the R&D Centre in Swords, Co Dublin. The R&D Centre has co-located technical and operational expertise, including analytical and engineering expertise that supports the development and manufacture of clinical and commercial products (small molecule APIs).
Position Description:
The Senior R&D Chemist will be responsible for providing strong scientific leadership for all aspects of new and existing chemical processes development, technology transfer, process scale-up, process monitoring, and process troubleshooting and optimisation for small molecules APIs and intermediates. Other responsibilities will include cross-functional team leadership and/or membership, authoring technical reports and leading/supporting Continuous Improvements activities. The role will involve significant cross functional collaboration with other functions including R&D, Operations, Quality, SHE, Supply Chain, PM
and external stakeholders working towards existing and new product introduction and ensuring all processes are understood, robust, efficient and in control.
Key responsibilities include:
· Provision of technical support on the design, development and improvement of process chemistry routes of synthesis (including synthetic route scouting and development of second generation processes).
· Provision of technical support to the manufacture of APIs and Intermediates manufactured at Swords.
· Drive, motivate and facilitate project teams, ensuring that timelines for R&D activities in support of scheduled campaign are achieved.
· Manage a team of chemists providing technical leadership, setting high performance standard and championing team’s personal development.
· Lead laboratory work to develop or improve manufacturing processes.
· Serve as Subject Matter Expert (SME) on products manufactured on site.
· Collaborate with internal and external stakeholders to support the development and the technology transfer of processes to Swords. Act as a key team member in the transfer of new processes throughout the tech transfer lifecycle from planning, process performance and post campaign support.
· Drive process robustness performance through process capability analysis. Use of this information and knowledge to contribute to comprehensive process verification reports and identification/execution of process robustness improvement projects, where required.
· Liaise with other departments on site (Quality, Supply Chain, PM, Procurement, Operations, SHE, Finance, and Engineering) to ensure efficient and robust chemical processes are executed on site.
· Interact with customers and wider SK network on a project or campaign basis to track progress of activities, identify continuous improvement opportunities and resolve issues
· Lead or support investigations, including statistical alert events, and provide coaching to chemists on process-related issues and identification of robust CAPAs through application of standard and statistical tools.
· Lead cost reduction projects, applying Lean tools and techniques to improve processing efficiency such as throughputs and yields.
· Ensure a culture of OpEx with the group and support the OpEx projects.
· Maintain focus on industry and technology trends and opportunities. Champion new technology for process understanding/monitoring and drive innovation/improvement on existing work practice (e.g. PAT, lab automation).
· Drive the development of appropriate specialist skills within R&D.
· Maintain/develop links with external networks including Universities & Industry groups.
· Drive continuous innovation, including second generation chemistry, innovative chemistry and promote industry best practice internally.
· Provide coaching, technical oversight and support for the activities of other chemist within the department. Support the development of other chemists on-site.
· Champion safe work practice.
· Support management of R&D laboratories.
· Assist in the recruitment, integration and training of chemists.
· Support budget planning activities
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