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Analytical Scientist

1 month ago

Cork, Cork, Ireland Eli Lilly and Company Full time
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Lilly's global purpose is to create medicines that make life better for people around the world. We help people get better, feel better, and live better. It's been our purpose for more than 140 years.

Within our Manufacturing and Quality organisation, we strive to hire talented, diverse and committed people to achieve our mission of delivering reliable supply of these innovative medicines to patients, with safety first and quality always. We are excited to offer new opportunities to technical candidates in the areas of Science, Engineering and Analytical to support our Drug Substance manufacturing facilities worldwide. This recruiting initiative allows us to recruit locally for a career opportunity in one of our US based organisations (Indiana). More detail on this focus will be provided through the interview process.

Outline of Role:

The Analytical Scientist role in Analytical Sciences/Quality Control Laboratories will be responsible for provision of analytical methods, data and information using advanced analytical mass spectrometry techniques in supporting individual site and network projects. This information may be structural or forensic in nature. It will involve analysis at ultra-trace levels. The development and validation of the methods and their associated lifecycle will be a key aspect of the role. The assets involved may be small molecules, peptides, therapeutic proteins, sRNAs, gene therapy and drug conjugates. These assets may be pipeline or commercial. The lifecycle management of existing technologies will be a further aspect of the role. Given the increasing need for more in-depth molecule information and the increasing complexity of assets, the identification of and implementation of new or improved technologies will be required. As all the information generated will be used to support manufacturing objectives, the active participation in cross functional teams will be required to understand manufacturing and regulatory requirements while also providing the analytical perspective to ensure overall success.

Key Responsibilities:

Analytical Sciences Support:

- Support the introduction, validation and on-going technical agenda for pipeline and commercial assets
- Develop and validate robust scientifically advanced methods with the required performance attributes to satisfy stakeholder needs
- Execute testing protocols in accordance with local procedure and regulatory requirements
- Develop strong links with Global Regulatory Affairs and participate in the preparation and review of regulatory submissions
- As required provide training or mentorship to other QC or cross functional team members
- Act as SME for mass spectrometry technologies and / or business systems within QC. This may include the identification, sourcing, installation, and qualification of new equipment

Leadership/ Site Management:

- Proactively support management decisions and strategy
- Be a role model for Analytical Sciences/Quality Control team members in terms of performance and behaviours
- Influence the Business/ external partners on critical issues to meet end goals – understand the external context/environment to achieve these goals
- Attend and contribute to relevant technical fora

Pre-Requisites:

- Candidates must be mobile to US based organizations after a defined qualification period at the recruiting site.

Job specific pre-requisites:

- Deep technical expertise in separation sciences, spectroscopy, hyphenated mass spectrometry techniques (MS and MSn) and their application particularly in the field of proteomics
- With safety as the priority excellent laboratory techniques
- Proficiency in the use of multiple instrument platforms (Thermo, Agilent, Waters etc.) and associated software platforms (Chromeleon, Excalibur)
- Strong technical problem-solving ability both independently and as part of a team
- Motivated to work independently to produce high quality work product in an efficient manner
- High attention to detail in all aspects of the work

Educational/Experience Requirements:

- Minimum PhD in Science
- Preferred 3-5 years of recent bench experience in a laboratory environment, relating to mass spectrometry

Additional Skills/Preferences:

- Strong written and oral communication skills
- Ability to work independently, self-sufficiently and pro-actively in the performance of work duties
- Ability to resolve conflict, and promote good decision making among team members
- High learning agility and flexibility to achieve the required outcomes
- Working knowledge in one or more of the following chemical, peptide or protein synthesis
- Development and implementation of multi-attribute methods (PAT or offline)
- Imaginative approach to problem solving and solution discovery

Key Attributes:

- Business Knowledge: High performance in delivery of their work. Looks at better, simpler ways, takes initiative and will run proactively with actions. Demonstrated self-management, prioritisation and organisational skills.
- Learning agility and Curiosity: High learning agility and flexibility and ability to deal with ambiguity and uncertainty. Demonstrated ability to identify and prioritize problems, develop and implement solutions.
- Positive Influence: Demonstrated ability to address issues as they arise and take action. Trusted in the team to follow through on actions. Is interested in own performance and seeks feedback to improve.
- Relationship Builder: Demonstrated ability to establish and maintain key relationships across all levels in the organisation.
- Ability to lead people: Demonstrated ability to lead and motivate in a team environment. Demonstrated ability to influence peers and across functions.
- Communication: Demonstrated strong communication skills, written and oral in 1:1 and group situations.
- Decision Making: Demonstrated ability to be decisive and make well informed decisions for the benefit of the team. Demonstrated ability to collate required information and ask the appropriate questions of peers to get to the best solution.

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