Upstream Process Development Scientist

10 hours ago


Dublin, Dublin City, Ireland Cpl Resources - TEG Full time

Cpl in partnership with our client Pfizer are seeking a Process Development Scientist to join the team for an 11 month contingent fixed term contract at their state of the art site in Dublin, Grange Castle. this is an on site role. What You Will Achieve As a Process development Scientist, you will be at the centre of our operations and youll find that everything we do, every day, is in line with an unwavering commitment to quality. You will provide science and technology expertise in the disciplines of cell culture sciences for the development and optimization ofprotein manufacturing processes. You will help Pfizer develop new and improved processes used in the research and development of our drugs. Your innovative mindset will help us develop economical, efficient and safe processes. Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. You are proactive in contributing to all team discussions and creating an environment of collaboration. It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe. How You Will Achieve It Pfizers Sterile Injectables and Biotech Technology (SBT) portfolio comprises multiple approaches for the creation of effective bio therapeutics. This laboratory-based role will focus on the characterisation and improvement of these processes for existent large molecules in commercial manufacturing, and in the later stages of development programs at Pfizer. Comply with safety and regulatory requirements is expected and documented through the internal training program. Develop and optimise robust cell culture processes via experimental investigations at 250 mL 750 L production scales. Operation of mammalian cell culture processes up to 750 L scale within the Pilot Lab according to pre-defined procedures. Apply knowledge of cell culture technologies, bioprocess engineering and biochemistry to cell culture process development projects. Collaborate closely with analytical scientists who work on the characterization of proteins during process development studies. Provide technical guidance such as direction of laboratory investigational studies, process and experimental design and new technology development. Provide technical support to Drug Substance Technical Services when required during investigations, new process introduction or change implementation in commercial manufacturing operations.Technical support may involve trouble-shooting manufacturing-scale process problems through experimental investigations at laboratory scales of operation. Qualifications & Skills BEng / BSc in Biotechnology / Chemistry / Chemical Engineering / Biochemical Engineering or other related disciplines with a minimum of 4 years of directly relevant experience in the biopharmaceutical industry, or MSc / MEng in Biotechnology / Chemistry / Chemical Engineering / Biochemical Engineering or other related disciplines with a minimum of 3 years of directly relevant experience in the biopharmaceutical industry, or PhD in Biotechnology / Chemistry / Chemical Engineering / Biochemical Engineering or other related disciplines with a minimum of 1 years of directly relevant experience in the biopharmaceutical industry Technical fields of experience preferably to include specific knowledge and practical experience of large molecule bio processing and separation sciences gained at a minimum at BEng or BSc level or through work experience Experience in designing and executing components of experimental programs in the laboratory. Familiar with problem-solving, risk analysis and/or statistical tools Behavioural/Values A team player by preference. An analytical thinker with a scientific curiosity and flair for laboratory experimentation. Highly motivated. Excellent communication skills (verbal, written). Demonstrate the Pfizer values and behaviours Courage, Excellence, Equity, Joy Adhere to all HR Policies as appropriate Proactive engagement with key stakeholders. Best practices developed and shared with other teams /sites. Best practices actively sought and copied. Proactive & effective communication within and across teams Work Location On premise Skills: Chemistry Chemical Engineering GMP HPLC Process Development upstream



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