PhD Organic Chemist
2 weeks ago
The role is site based onsite in Swords, Co. DublinContact Jenn Dinan on 01 4408352 and emailPhD Organic Chemist -Permanent - Dublin A vacancy now exists for a PhD Chemist within the R&D group. This position is based at the R&D Centre in Swords, Co Dublin. The R&D Centre has co-located technical and operational expertise, including analytical expertise that supports the development and manufacture of clinical and commercial products (small molecule APIs).The R&D Chemist will have experience in synthetic organic chemistry. They will be responsible for providing support for all aspects of new and existing chemical processes development, technology transfer, process scale-up, process safety, process monitoring, and process troubleshooting for small molecules.The role will involve cross functional collaboration with other functions including Operations, Quality, EHS and external stakeholders working towards existing and new product introduction and ensuring all processes are understood, robust, efficient and in control. Essential Responsibilities: * Lead development projects in the laboratory, including route scouting and route development, proof of concept, crystallisation optimisation, and process safety assessment. * Provide technical support to the manufacture of APIs and intermediates with a focus on optimisation and investigation support. * Identify and implement projects to optimise processes, considering scale-up and manufacturing aspects and Critical to Quality Attributes. * Leverage data monitoring and PAT tools in the laboratory such as FBRM, Raman, IR, as required. Identify and implement new technologies to support development for the business needs of the site. * Coordinate tech transfer activities for introduction of new clinical and commercial products to the site, including process development in the laboratory, customer engagement, troubleshooting, documentation, and campaign readiness. * Support chemistry assessments for new products as required. * Lead optimisation projects on throughput and yield in collaboration with Operations engineers. * Support continuous process verification through collection and trending of data for commercial products, identifying Out of Trends (OOT) and Statistical Alert Events (SAE) and leading investigations where required with support from R&D engineers and analytical chemists. * Actively participate in manufacturing campaign performance support teams. * Lead and support quality and safety investigations. * Collaborate with R&D analytical chemists and Operations engineers on new products introduction and scale up activities Minimum Requirements: * Strong technical background in chemistry. * PhD in organic chemistry. * 3 years of experience in the pharmaceutical industry * Strong interpersonal and communicational skills and demonstrated ability to work across a matrix. * Excellent problem solving skills and commitment to continuous improvement. * Experience in project management, troubleshooting and continuous process verification. * Demonstrated capability in the use of standard tools for root cause analysis and standard statistical tools. * Demonstrated capability in the use of various analytical/diagnostic tools including PAT, chromatography and process safety. * Ensure that GMP, Quality, Health & Safety are considered in all aspects of the role. Other Benefits Include: * Excellent opportunities for career enhancement and personal development. * Competitive base salary. * Annual bonus linked to business results. * A well-established further education program. * Pension scheme. * Private healthcare.All applications will be treated with the strictest of confidenceContact JENN DINAN on or call 01 4408352At Wallace Myers International Recruitment Agency we specialise in sourcing professionals for key industries and services.
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