Post-Doctoral Researcher APC Microbiome Ireland
19 hours ago
Organisation/Company: University College Cork
Department: HR Research
Research Field: Medical sciences » Other
Researcher Profile: Established Researcher (R3)
Positions: PhD Positions
Country: Ireland
Application Deadline: 20 Sep 2024 - 12:00 (Europe/Dublin)
Type of Contract: Temporary
Job Status: Full-time
Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure? No
Offer DescriptionPosition Summary
Aburto Lab at APC Microbiome Ireland/Dept. of Anatomy and Neuroscience wish to recruit a Post-Doctoral Researcher.
The project aims to understand how gene x environment interactions, such as host genetics and gut microbiota modulate CNS vascularisation and neurovascular interactions. We will use in vivo models (mouse) where we will perform different gut microbiota manipulations, both in wild-type mice as well as in different autism-spectrum disorder mouse models. The appointee will be focusing on performing RNA sequencing of brain endothelial cells during embryonic and postnatal development and brain and plasma metabolomics to understand how microbial signals could modulate vascular and neurovascular processes. They will also be involved in confocal microscopy and in vitro models (e.g., tube formation assay or blood-brain barrier in vitro models).
Experience in mouse handling, confocal microscopy, molecular and computational biology such as RNA sequencing data analysis and metabolomics analysis datasets will be highly valued.
The appointee will work directly with the Aburto Lab group. Our work focuses on the role of the gut microbiota in brain development and main techniques we use are mouse experiments with microbiota manipulations, brain histology, immunofluorescence, RNA extraction and analysis, cell culture, tissue culture and microscopy. Experience in these disciplines will be highly valued. For more information on what we do please visit aburto-lab.org .
Project Title: Deciphering the role of early life microbiota in neuro-glia-vascular development and contributions to neurodevelopmental disorders.
Post Duration: 20 Months
The primary focus of the Postdoctoral Researcher will be research; however, a particular emphasis during this stage should include:
- To conduct a specified programme of research under the supervision and direction of a Principal Investigator/Project Leader.
- To engage in appropriate training and professional development opportunities as required by the Principal Investigator, School or College in order to develop research skills and competencies.
- To gain experience in grant writing.
- To engage in the dissemination of the results of the research in which they are engaged, as directed by, with the support of and under the supervision of a Principal Investigator.
- To become familiar with the publication process.
- To acquire generic and transferable skills (including project management, business skills and postgraduate mentoring/supervision).
- To engage in the wider research and scholarly activities of the research group, School or College.
- To interact closely with postgraduate research students who are studying for a Masters or a PhD and possibly have an agreed role in supporting these students in their day to day research in conjunction with an academic supervisor.
- To carry out administrative work to support the programme of research.
- To carry out additional duties as may reasonably be required within the general scope and level of the post.
- To contribute to costing research grant proposals and assist in the financial management of a research project.
Specific Requirements:
- Appropriate research experience.
- Appropriate technical competence and accomplishment.
- A capability of working within a project team to achieve results.
- Good communication, organisation and interpersonal skills.
- A commitment to gaining practical experience working on a research project.
- Ability to work well within a team.
- The successful candidate will be required to contribute to the APC’s Public Engagement programme, by being involved in science related dissemination activities for the public and schools.
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