Senior Bioprocess Upstream Development Scientist
3 weeks ago
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APC Ltd is an award-winning science and technology driven biopharmaceutical process research company. In the space of 5 years, we have pioneered innovation in the sector and we now partner with 8 of the top 10 pharma and 5 of the top 10 biotech firms in the world, and we continue to grow.
From our world-class facility, we offerspecialised bioprocess engineering solutions. Powered by novel technology and world-class scientific research, we help companies accelerate the development & launch of their medicines.
Our rapid growth has come from a commitment to excellence, a drive to innovate and the desire to develop a challenging, creative and rewarding environment for our team. If you are interested in a career focused on technical innovation, process design and impact,we would love to hear from you.
About The Team
Department: Technical Operations
Reports to:USP Functional Lead
Our biologics team comprises of highly qualified, dynamic and welcoming colleagues.We support our clients by delivering world class bioprocess development to accelerate the delivery of quality, life-changing medicines to the patient across a wide range of therapeutic areas from oncolytic vaccines to rare genetic diseases.
Our team vision is to enhance the bioprocess development experience for our clients in a dynamic and cross-collaborative environment (APC Engineering, APC Biologics, APC Analytical, APC Quality & VLE GMP Manufacturing)
If you are looking to start your career in a dynamic, creative and patient focussed environment then APC is for you.
Principal Duties and Objectives
- Operate to GLP standards (adherence to APCs Safety and Quality Systems) within a R&D laboratory
- Provide R&D laboratory support across the APC Bioprocess Development department through collaboration with other scientists, analysts and engineers, both internally and externally
- Working within a research team to plan, organise and execute R&D biopharmaceutical research projects
- Support the tech transfer, development and/or optimization across a wide range of cell-lines (human, mammalian, avian, microbial) and platforms processes (adherent/suspension/microcarrier/perfusion).
- Facilitate the development of biopharmaceutical scale-up strategies for biological-based processes to our non-GMP single-use pilot plant and to VLE's GMP manufacturing suite.
- Support the development and introduction of new techniques, methods and processes to improve business effectiveness, as required
- Prepare/Support the preparation of technical presentations and process development/deviation reports
- Facilitate the discussion of issues, results and project progress with client companies and management
- Support critical lab and equipment maintenance.
- Minimum of 5+ years' pharma industry experience in Upstream process development (if PhD qualified); or
- Minimum of 7+ years' pharma industry experience in Upstream process development (if MSc qualified); or
- Minimum of 10+ years' pharma industry experience in Upstream process development (if BSc/BE qualified).
- The Senior scientist will act as technical supervisor of multiple projects, and he will be accountable for the technical performance & delivery of the assigned projects.
- Hands-on experience with laboratory and/or pilot scale bioreactors
- Ability to work in a dynamic and multidisciplinary environment.
- Ability to write and follow an experimental protocol.
- Demonstrated experience in cell culture techniques for suspension culture systems.
- Self-motivated with a "can-do" attitude.
- Good technical writing skills and previous technical presentation experience.
- Ability to disseminate information to research team and directors.
- Excellent technical skills (Hands on multiple scale Bioreactor process experience ) including troubleshooting
- Hands-on experience with either process design, process development, process characterisation or MS&T
- Excellent communication, negotiation and inter-personal skills as well as Project management skills
- Experience with multiple modalities is preferred
Suitable candidates should submit a CV and a Cover Letter by close of business 13th June 2025
APC is committed to the principle of equal opportunity for all employees.All employment decisions at APC are based on business needs, job requirements and individual qualifications, without regard to gender, ethnicity, age, religious belief, disability, sexual orientation, gender identity and/or expression, marital status, or any other status protected by Irish law.
Similar vacancies arising in the coming 6 months may be filled from this group of applicants.Seniority level
- Seniority levelNot Applicable
- Employment typeFull-time
- Job functionResearch, Analyst, and Information Technology
- IndustriesPharmaceutical Manufacturing
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