▷ 3 Days Left Upstream Scientist

1 week ago

Dublin Pike, Ireland Russell Tobin Full time

Overview Job Title : Scientist – Upstream and/or Downstream
Location : Dublin
Contract Type : 12 Month Contract
Position Summary A leading biopharmaceutical facility in Dublin is seeking a Contract Manufacturing Technology (MT) Scientist to support upstream and/or downstream operations within a commercial-scale biologics manufacturing environment. The MT team is responsible for process validation and providing technical support for the manufacture of mammalian cell culture processes. This role offers the opportunity to contribute to a dynamic and technically driven team, collaborating closely with Manufacturing, Engineering, Quality, and Regulatory functions.
Key Responsibilities Apply scientific knowledge to commercial drug substance manufacturing in one or more of the following areas:
Upstream (Cell Culture): Media preparation, vial thaw, scale-up, single-use systems, seed/production bioreactors, harvest centrifugation/clarification.
Downstream (Purification): Buffer preparation, chromatography, viral reduction/inactivation, ultrafiltration, formulation, and bulk fill.
Author and review technical documents including protocols, reports, and SOPs supporting manufacturing process validation and technical studies.
Use data analytics tools to assess process performance and identify opportunities for improvements (e.g., yield, cycle time).
Lead the preparation and execution of plant support and technical studies at commercial scale.
Provide on-the-floor support for troubleshooting and resolving technical issues, including leading investigations into process deviations.
Act as a process subject matter expert during regulatory inspections and audits.
Communicate technical insights, findings, and best practices through internal presentations or external scientific forums.
Support process improvements, CAPA implementation, and Lean initiatives across the manufacturing site.
Qualifications & Experience Minimum of a BSc or equivalent in a relevant scientific discipline.
At least 2 years of experience in drug substance manufacturing technical support within the biopharmaceutical industry.
Solid understanding of cGMP , validation requirements, and regulatory compliance expectations.
Strong technical writing and communication skills, with the ability to present and defend scientific approaches.
Collaborative mindset with the ability to operate effectively in cross-functional and matrixed teams.
Demonstrated ability to influence and engage stakeholders across multiple functions.
Additional Requirements This role may occasionally require extended hours, modified shift patterns, or on-call availability.
Apply Apply now to take the next step in your biopharmaceutical career.
This is a contract role based in Dublin.

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