Evidence Synthesis Expert

2 weeks ago

Dublin, Dublin City, Ireland beBeeStatistician Full time €75,000 - €105,000
Senior Statistician for HTA and Clinical Research

We are seeking a highly experienced Senior Statistician to apply innovative statistical approaches to complex challenges in health technology assessment (HTA) and clinical research.

This role leads the evidence synthesis of patient data from clinical, observational, and real-world studies to support HTA submissions in a collaborative environment.

The position involves leading the design and execution of evidence synthesis for HTA submissions, including EU HTA JCA Dossiers and health economic models, applying methodological and analytical expertise to demonstrate the value of our assets and communicate findings to external decision makers.

Main Responsibilities:

  • Develop global Indirect Treatment Comparison plans for HTA, payer, and other Access stakeholder assessments, submissions, and negotiations.
  • Lead publications associated with these to meet business objectives.
  • Provide strategic, methodological, and analytical support to regions and top countries with adaptation of the ITC for local HTA submissions and support the local assessment of HTA strategy.
  • Coordinate data requirements across evidence generations functions to support Pricing & Reimbursement.
  • Set up systems internally to proactively capture key HTA analytic requirements across key international markets to inform and optimize key internal deliverables.
  • Track key HTA statistics priorities and sequence them aligning with resource availability and risks.
  • Identify the need for preliminary ITCs to inform value proposition, development, pricing, and commercial strategic forecast and decisions.
  • Lead and facilitate the sharing of best practices and key learnings across regions, countries, and cross-functional partners.
  • Stay on top of innovative techniques, using robust analytical techniques to leverage available clinical data and published information to inform pricing and market access strategy.
  • Collaborate with the Biostats team for trial analyses, HTA challenges, and statistical analyses.
  • Act as a Strategic Partner for key partners from HEOR & PCO and International Value & Access to ensure alignment to brand and commercial, access, and evidence strategy.
  • Ensure optimal utilization of comparative evidence through partnership with teams generating payer & promotional materials, generating regulatory dossiers, and publications.
  • Provide mentoring and coaching support to junior members of evidence modelling teams and across function.

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