
Research and Development Scientist
2 weeks ago
We are seeking an experienced R&D PhD Chemist to join our team on a temporary basis. The successful candidate will have a strong technical background in chemistry and a PhD in organic chemistry.
Job Description:
The R&D PhD Chemist will be responsible for providing support for all aspects of new and existing chemical processes development, technology transfer, process scale-up, process safety, process monitoring, and process troubleshooting for small molecules.
This role will involve cross-functional collaboration with other functions including Operations, Quality, Health & Safety, and external stakeholders working towards existing and new product introduction and ensuring all processes are understood, robust, efficient, and in control.
Main Responsibilities:
- Lead development projects in the laboratory, including route scouting and route development, proof of concept, crystallisation optimisation, and process safety assessment.
- Provide technical support to the manufacture of APIs and intermediates manufactured at our site, with a focus on optimisation and investigation support.
- Identify and implement projects to optimise processes, considering scale-up and manufacturing aspects and Critical to Quality Attributes.
- Leverage data monitoring and PAT tools in the laboratory such as FBRM, Raman, IR, as required.
- Collaborate with R&D analytical chemists and Operations engineers on new products introduction and scale-up activities, including process development in the laboratory, customer engagement, troubleshooting, documentation, and campaign readiness.
- Support chemistry assessments for new products as required.
- Lead optimisation projects on throughput and yield in collaboration with Operations engineers.
- Support continuous process verification through collection and trending of data for commercial products, identifying Out of Trends (OOT) and Statistical Alert Events (SAE) and leading investigations where required with support from engineers and analytical chemists as required.
- Actively participate in manufacturing campaign performance support teams.
- Lead and support quality and safety investigations.
Requirements:
- Strong technical background in chemistry.
- PhD in organic chemistry.
- Strong interpersonal and communicational skills and demonstrated ability to work across a matrix.
- Excellent problem-solving skills and commitment to continuous improvement.
- Experience in project management, troubleshooting, and continuous process verification.
- Demonstrated capability in the use of standard tools for root cause analysis and standard statistical tools.
- Demonstrated capability in the use of various analytical/diagnostic tools including PAT, chromatography, and process safety.
- Ensure that GMP, Quality, Health & Safety are considered in all aspects of the role.
About Us:
We believe that we enhance patients' lives and we need you. Our mission is to make what matters for a healthy, happier world - whatever your title, whatever your role, you act as a catalyst in a chain of events that helps millions of people all over the globe.
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